Meniscal allograft transplantation
Meniscal allograft transplantation is surgery in which a meniscus -- a c-shaped cartilage in the knee -- is placed into your knee. The new meniscus is taken from a person who has died (cadaver) and donated their tissue.
Description
If your surgeon finds that you are a good candidate for a meniscus transplant, x-rays or an MRI of your knee are usually taken to size your knee in order to find a meniscus that will fit your knee. The donated meniscus is tested in the lab for any diseases and infection.
MRI
A magnetic resonance imaging (MRI) scan is an imaging test that uses powerful magnets and radio waves to create pictures of the body. It does not us...
Read Article Now Book Mark ArticleOther surgeries, such as ligament or cartilage repairs, may be done at the time of the meniscus transplant or with a separate surgery.
You will likely receive general anesthesia before this surgery. This means you will be asleep and unable to feel pain. Or, you may have regional anesthesia. Your leg and knee area will be numbed so that you do not feel any pain. If you receive regional anesthesia, you will also be given medicine to make you very sleepy during the operation.
During the surgery:
- The meniscus transplant is usually performed using knee arthroscopy. The surgeon makes two or three small cuts around your knee. Salt water (saline) will be pumped into your knee to inflate the knee.
Knee arthroscopy
Knee arthroscopy is surgery that uses a tiny camera to look inside your knee. Small cuts are made to insert the camera and small surgical tools into...
Read Article Now Book Mark Article - The arthroscope is inserted into your knee through a small incision. The scope is connected to a video monitor in the operating room.
- The surgeon inspects the cartilage and ligaments of your knee, confirming that a meniscus transplant is appropriate and that you don't have severe arthritis of the knee.
- The new meniscus is prepared to fit your knee correctly.
- If any tissue is left from your old meniscus, it is removed.
- The new meniscus is inserted into your knee and sutured (sewn) in place. Screws or other devices may be used to hold the meniscus in place.
After the surgery is finished, the incisions are closed. A dressing is placed over the wound. During arthroscopy, most surgeons take pictures of the procedure from the video monitor to show you what was found and what was done.
Why the Procedure Is Performed
Menisci are two cartilage rings that are in each knee. One is on the inner side of the knee (medial meniscus) and one is on the outer side (lateral meniscus). When a meniscus is torn, it is commonly removed by knee arthroscopy. Some people can continue to have pain after the meniscus is removed. The loss of meniscus can also lead to early osteoarthritis but the transplant can help slow down the degeneration that causes osteoarthritis.
A meniscus transplant places a new meniscus in the knee where the meniscus is missing. This procedure is only done when meniscus tears are so severe that all or nearly all of the meniscus cartilage is torn or has to be removed. The new meniscus can help with knee pain and possibly prevent future arthritis.
Meniscus allograft transplantation may be recommended for knee problems such as:
- Development of early arthritis
- Inability to play sports or other activities
- Knee pain
- Knee that gives way
- Unstable knee
- Persistent knee swelling
Risks
Risks of anesthesia and surgery in general are:
-
Allergic reactions to medicines
Allergic reactions
Allergic reactions are sensitivities to substances called allergens that come into contact with the skin, nose, eyes, respiratory tract, and gastroin...
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Problems breathing
Problems breathing
Breathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough air
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Bleeding, blood clots, infection
Bleeding
Bleeding is the loss of blood. Bleeding may be:Inside the body (internal)Outside the body (external)Bleeding may occur:Inside the body when blood le...
Read Article Now Book Mark ArticleBlood clots
Blood clots are clumps that occur when blood hardens from a liquid to a solid. A blood clot that forms inside one of your veins or arteries is calle...
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Risks of meniscal transplant surgery are:
- Nerve damage
- Stiffness of the knee
- Failure of the surgery to relieve symptoms
- Failure of the meniscus to heal
- Tear of the new meniscus
- Disease from the transplanted meniscus
- Pain in the knee
- Weakness of the knee
Before the Procedure
- You are or could be pregnant
- You are taking any medicines, including medicines, drugs, supplements, or herbs you bought without a prescription
During the 2 weeks before your surgery:
- You may be asked to temporarily stop taking blood thinners. These include aspirin, ibuprofen (Advil, Motrin), naproxen (Naprosyn, Aleve), and other medicines.
- Ask your surgeon which medicines you should still take on the day of your surgery.
- If you have diabetes, heart disease, or other medical conditions, your surgeon will ask you to see your health care provider who treats you for these conditions.
Diabetes
Diabetes is a long-term (chronic) disease in which the body cannot regulate the amount of sugar in the blood.
Read Article Now Book Mark ArticleHeart disease
Coronary heart disease is a narrowing of the blood vessels that supply blood and oxygen to the heart. Coronary heart disease (CHD) is also called co...
Read Article Now Book Mark Article - Tell your provider if you have been drinking a lot of alcohol, more than 1 or 2 drinks a day.
- If you smoke, try to stop. Ask your provider for help. Smoking can slow wound and bone healing.
Smoke, try to stop
There are many ways to quit smoking. There are also resources to help you. Family members, friends, and co-workers may be supportive. But to be su...
Read Article Now Book Mark ArticleSmoking can slow wound and bone healing
Quitting smoking and other nicotine products, including e-cigarettes, before surgery can improve your recovery and outcome after surgery. Most people...
Read Article Now Book Mark Article - Let your surgeon know about any illness you may have before your surgery. This includes COVID-19, a cold, flu, fever, herpes outbreak, or other illness. If you do get sick, your surgery may need to be postponed.
COVID-19
Coronavirus disease 2019 (COVID-19) is a respiratory illness that causes fever, coughing, and shortness of breath, but many other symptoms can occur....
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The common cold most often causes a runny nose, nasal congestion, and sneezing. You may also have a sore throat, cough, headache, or other symptoms....
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The flu (influenza) is a viral respiratory illness that causes fever, chills, runny nose, body aches, and cough. It spreads easily from person to pe...
Read Article Now Book Mark Article - If needed, prepare your home to make it easier to recover after surgery.
Prepare your home
Getting your home ready after you have been in the hospital often requires some preparation. Set up your home to make your life easier and safer when...
Read Article Now Book Mark Article - Ask your surgeon if you need to arrange to have someone drive you home after your surgery.
On the day of surgery:
- Follow instructions on when to stop eating and drinking before the surgery.
- Take the medicines your provider told you to take with a small sip of water.
- Follow instructions on when to arrive at the hospital. Be sure to arrive on time.
After the Procedure
Follow any discharge and self-care instructions you are given.
Discharge
You had arthroscopy to treat problems in your knee. This article discusses how to take care of yourself when you go home from the hospital.
Read Article Now Book Mark ArticleAfter the surgery, you will probably wear a knee brace for the first 6 weeks. You will need crutches for 6 weeks to prevent putting full weight on your knee. You will likely be able to move the knee right after surgery. Doing so helps prevent stiffness. Pain is usually managed with medicines.
Physical therapy can help you regain the motion and strength of your knee. Therapy lasts for between 4 and 6 months.
How soon you can return to work depends on your job. It can take from a few weeks to a few months. It can take 6 months to a year to fully return to activities and sports.
Outlook (Prognosis)
Meniscus allograft transplantation is a difficult surgery, and the recovery is hard. But for people who are missing the meniscus and have pain, it can be very successful. Most people have less knee pain after this procedure.
Reviewed By
C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Phillips BB, Mihalko MJ. Arthroscopy of the lower extremity. In: Azar FM, Beaty JH, eds. Campbell's Operative Orthopaedics. 14th ed. Philadelphia, PA: Elsevier; 2021:chap 51.
Ruzbarsky JJ, Maak TG, Rodeo SA. Meniscal injuries. In: Miller MD, Thompson SR, eds. DeLee, Drez & Miller's Orthopaedic Sports Medicine: Principles and Practice. 5th ed. Philadelphia, PA: Elsevier; 2020:chap 94.
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